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4.1 Dental Sealant Material Selection

Bisphenol-A

BPA is a chemical commonly used in the manufacturing process of certain plastics. BPA can be found in the lining of food cans and toys. In dentistry, BPA may be found in some dental sealant materials, and, to a lesser extent, in dental composite resin filling materials.8

There has been concern about BPA because of widespread human exposure and the potential of BPA to bind to estrogen receptors of relevant cells in cell cultures, impairing the development and reproductive systems of some animals.9 However, although BPA may affect health in animals, to date, no effects have been observed in humans. There is debate over the level of exposure that might pose a risk to humans.8

BPA may be present as an impurity in some dental resins or as a degradation product in others. Several chemical and mechanical factors, including the exposure of some dental resin filling materials to saliva, may result in their slow and persistent degradation and in BPA release. BPA has been detected in saliva samples in individuals following the application of one specific dental sealant material (i.e., Delton LC) for up to 3 hours after application, but it is possible that BPA is not absorbed by the body, or it may be present in undetectable amounts in circulation.10

A systematic review of the scientific literature investigating whether sealant placement causes toxicity concluded that the evidence suggests that individuals are not at risk for BPA exposure from sealants.9